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<journal-meta>
<journal-id pub-id-type="pid">S1409-009020010003</journal-id>
<journal-title>Acta Pediátrica Costarricense</journal-title>
<abbrev-journal-title>Acta pediátr. costarric</abbrev-journal-title>
<issn>1409-0090</issn>
<publisher>
<publisher-name>Asociación Costarricense de Pediatría</publisher-name>
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</journal-meta>
<article-meta>
<article-id>S1409-00902001000300001</article-id>
<title-group>
<article-title xml:lang="es">Manejo de la meningitis por Streptococcus pneumoniae en una era de resistencia a la penicilina</article-title>
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<institution>,CCSSS Hospital Nacional de Niños Servicio de Infectología</institution>
<addr-line>San José </addr-line>
<country>Costa Rica</country>
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<pub-date pub-type="pub">
<year>2001</year>
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<volume>15</volume>
<fpage>90</fpage>
<lpage>94</lpage>
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<self-uri xlink:href="http:/www.scielo.sa.cr/scielo.php?script=sci_arttext&amp;pid=S1409-00902001000300004&amp;lng=en&amp;nrm=iso&amp;tlng=en"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_abstract&amp;pid=S1409-00902001000300004&amp;lng=en&amp;nrm=iso&amp;tlng=en"></self-uri><self-uri xlink:href="http://www.scielo.sa.cr/scielo.php?script=sci_pdf&amp;pid=S1409-00902001000300004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p>Objetivo: Analizar los datos de pacientes hospitalizados con infecciones por Adenovirus durante una epidemia observada en el Hospital Nacional de Niños &quot;Dr. Carlos Sáenz Herrera&quot; (HNN) de octubre de 1999 a marzo del 2000. Diseño: Estudio retrospectivo y descriptivo. Materiales y métodos: Se revisaron los expedientes de pacientes hospitalizados en el HNN con inmunofluorescencia viral positiva por Adenovirus durante el periodo descrito. Resultados: Cuarenta y seis pacientes se hospitalizaron con el diagnóstico de infección por Adenovirus. Todos los pacientes fueron menores de 4 años y seis meses, con una edad promedio de 12.7 meses. Predominó el sexo masculino. El 71,7% de los pacientes ya habían tenido hospitalizaciones previas. Se identificó que el tener enfermedades como displasia broncopulmonar, reflujo gastroesofágico, oxígenodependencia e hipertensión pulmonar, aumenta el riesgo de tener complicaciones como la ventilación mecánica y la mortalidad. El 68,9% de los pacientes tenían un estado nutricional normal. Los diagnósticos de ingreso más frecuentes fueron bronconeumonía, bronquiolitis, y diarrea. Los síntomas y signos más frecuentes al ingreso fueron fiebre, dificultad respiratoria y tos. La mayoría (93,5%) requirió oxígeno desde el ingreso, el 54% de los pacientes ameritaron ventilación mecánica, un 71,7% esteroides sistémicos, un 80,4% broncodilatadores y un 89,1% antibióticos. La proteína c reactiva, las concentraciones absolutas de leucocitos, neutrófilos y bandas se elevaron durante las infecciones por adenovirus. Las complicaciones más frecuentes fueron ventilación mecánica, choque séptico, bronquiolitis obliterante y bronconeumonía. Un 28,2% de los pacientes fallecieron. Conclusiones: Los lactantes mayores, el sexo masculino, el antecedente de hospitalizaciones previas y el tener alguna enfermedad crónica asociada constituyen factores de riesgo para infecciones por adenovirus. La morbimortalidad aumenta principalmente en pacientes con enfermedades pulmonares de fondo. Los exámenes de laboratorio pueden confundir la infección por adenovirus con infecciones bacterianas. Las complicaciones fueron infecciosas y pulmonares principalmente. Estas infecciones pueden tener una mortalidad alta.</p></abstract>
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<kwd>Infección por adenovirus</kwd>
<kwd>epidemiología</kwd>
<kwd>complicaciones</kwd>
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<kwd>morbimortalidad</kwd>
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<article-meta>
<article-id>S1409-00902001000300005</article-id>
<title-group>
<article-title xml:lang="es">Enteropatía perdedora de proteínas: reporte de dos casos y revisión bibliográfica</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Gamboa</surname>
<given-names>Ana Yéssika</given-names>
</name>
<xref ref-type="aff" rid="A01"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mora Guevara</surname>
<given-names>Alfredo</given-names>
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</contrib>
<contrib contrib-type="author">
<name>
<surname>Calvo Espinoza</surname>
<given-names>Mónica</given-names>
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<aff id="A01">
<institution>,C.C.S.S. Residente de tercer año de Pediatría </institution>
<addr-line> </addr-line>
</aff>
<pub-date pub-type="pub">
<year>2001</year>
</pub-date>
<pub-date pub-type="epub">
<year>2001</year>
</pub-date>
<volume>15</volume>
<fpage>120</fpage>
<lpage>123</lpage>
<copyright-statement/>
<copyright-year/>
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